CONTRAST AGENTS
Iris

CONTRAST AGENTS

Since the early days of magnetic resonance imaging (MRI) development, contrast media has played an important role in optimizing the clinical benefit that MRI is able to provide in medical imaging.2

Mohammed Ouchen

VIDEO

Although the challenges of bringing a new pharmaceutical product to market are well known, what is sometimes surprising is that manufacturing pharmaceutical products at a commercial scale is not always the easy part.

Sit down with Mohammed Ouchen, Industrial Project Manager at Guerbet, to hear a story of constant improvement in production processes.

 

DRUGS (2)

ARTICLE

Challenges of drug manufacturing

Although the challenges of bringing a new pharmaceutical product to market are well known, what is sometimes surprising is that manufacturing pharmaceutical products at a commercial scale is not always the easy part. 

Read the article to learn more on the challenges of drug manufacturing.  

Vignette Looking To The Future 1192X894

ARTICLE

CONTRAST AGENTS: UNMET NEEDS & INNOVATIONS

Although several metal-based agents have been explored over the years, gadolinium-based contrast agents (GBCAs) have come to dominate the contrast-enhanced MRI (CE-MRI) market since their introduction in the late 1980s.1,2

Read the full article

Infographic Contrast Agent 1192X894

INFOGRAPHIC

INNOVATIONS IN MRI ENHANCEMENT1

Areas for innovation in MRI enhancement include metalbased and metal- free contrast media, as well as technological advances that could require no contrast agent at all.

1- Minton LE, Pandit R, Willoughby WR, Porter KK. The future of magnetic resonance imaging contrast agents. Appl Radiol. 2022:7-11.

Open the infographic

Vignettes Videos2

VIDEO

SUMMONING THE FUTURE OF MRI AT GUERBET

Hear from Sarah Catoen, Global Discovery Director at Guerbet, about how Guerbet is helping to advance the state of the art.

Vignette Reasons For Reducing 1192X894

ARTICLE

REASONS FOR REDUCING THE DOSE OF GADOLINIUM (GD), NOW AND IN THE FUTURE

Since their introduction in 1988, Gd-based contrast agents have been used in hundreds of millions of patients.1,2 But with the emergence of rare but potentially severe side effects, efforts have been undertaken to optimize patient safety.2,3 These are outlined here.

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References

  1. Viard A, Eustache F, Segobin S. History of magnetic resonance imaging: a trip down memory lane. Neuroscience. 2021;474:3-13.
  2. de Haën C. Conception of the first magnetic resonance imaging contrast agents: a brief history. Top Magn Reson Imaging. 2001;12(4):221-230.
  3. Forcinio H. Innovations meet growing demand for prefilled syringes. BioPharm Int. 2021;36:32-35.
  4. Börnert P and Norris DG. A half-century of innovation in technology—preparing MRI for the 21st century. Br J Radiol. 2020;93(1111):20200113.
  5. Ai T, Morelli JN, Hu X, et al. A historical overview of magnetic resonance imaging, focusing on technological innovations. Invest Radiol. 2012;47:725-741.
  6. López-Sánchez J, Santos-Vijande ML. Key capabilities for frugal innovation in developed economies: insights into the current transition towards sustainability. Sustain Sci. 2022:1-17.
  7. Liu Y, Leong ATL, Zhao Y, et al. A low-cost and shielding-free ultra-low-field brain MRI scanner. Nat Commun. 2021;12(1):7238.